Studies

Note : medications like finasteride and dutasteride are also used in case of BPH and there is a strong link between BPH and AGA.

Pygeum africanum bark extract has been used in France since 1969 to treat mild to moderate symptoms of an enlarged prostate (BPH). The extract has properties that can help with bladder muscle issues, inflammation, and prostate health. Studies involving 2262 patients over 25 years show that the extract is effective and well-tolerated, with most patients experiencing good outcomes.

It has advantages over some other proposed drugs for BPH, and its safety profile is excellent. Considering the renewed interest in non-surgical BPH treatments, further research comparing Pygeum africanum extract with other drug classes may be beneficial.

Note : medications like finasteride and dutasteride are also used in case of BPH and there is a strong link between BPH and AGA.

This study looked at whether an extract from the African prune tree, Pygeum africanum, is effective in treating an enlarged prostate (BPH). They wanted to know if it works better than a placebo, if it’s as good as standard medications for BPH, and if it causes fewer side effects.

They searched various databases and found 18 studies involving 1562 men. The results suggest that Pygeum africanum can moderately improve urinary symptoms and flow compared to a placebo. It also seems to reduce symptoms like nocturia (nighttime urination) and increase peak urine flow. Side effects were mild and similar to a placebo. However, the studies were small, short-term, and used different doses, so more research is needed for conclusive evidence.

Note : medications like finasteride and dutasteride are also used in case of BPH and there is a strong link between BPH and AGA.

Pygeum africanum extracts are used to treat men’s health issues like prostatitis, benign prostatic hyperplasia (BPH), and prostate cancer. The human androgen receptor (AR) plays a role in prostate gland growth, and inhibiting it is a key treatment strategy.

Atraric acid (AA) from Pygeum africanum has anti-androgenic properties, specifically inhibiting the AR’s activity without affecting related receptors. AA hinders the nuclear transport of AR, suppressing the growth of both androgen-dependent and -independent prostate cancer cells.

This suggests AA could be a natural anti-androgenic compound and a potential basis for developing new therapeutic compounds for prostatic diseases.

In this study, a dietary supplement called RJ-SP4AGA containing a lipid co-extract from Serenoa repend and Pygeum africanum has been tested on post-menopausal women with AGA.

Results showed a significant reduction in telogen phase hair compared to placebo.