Japanese Ramie
Japanese ramie, scientifically known as Boehmeria nipononivea, is a perennial plant native to Japan. It is valued for its strong and durable fibers, which have been traditionally used for making textiles. The plant’s leaves and stems are covered in fine hairs, giving it a distinctive appearance.
In the realm of alopecia, Japanese ramie remains virtually unheard of in both Europe and the USA.
Is it effective against hair loss?
Currently, our knowledge and scientific research on the application of topical Japanese ramie for addressing hair loss are quite limited.
The complete composition of Japanese ramie extracts or oils is challenging to ascertain due to the scarcity of available information. However, based on the available data, it appears that these extracts contain a minimum of 25-30% fatty acids, which include alpha-linolenic, linoleic, palmitic, elaidic, oleic, and stearic acids.
Anti-androgen properties
As previously mentioned, Japanese ramie is found to contain a minimum of 30% fatty acids and a variety of other constituents. A 2000 study conducted by K. Shimizu and colleagues revealed that Japanese ramie extract exhibits significant inhibitory effects on 5-alpha reductase (5aR), which are slightly less potent than finasteride.
This suggests that applying it topically might be a promising approach to reduce DHT levels and potentially offer a practical solution for androgenetic alopecia.
Dihydrotestosterone (DHT) is a natural androgenic hormone synthesized by our bodies from testosterone in various tissues. This conversion is mediated by an enzyme called 5-alpha-reductase (5aR).
DHT is a significant factor in androgenetic alopecia, as it plays a role in the inflammatory process occurring in the scalps of individuals genetically predisposed to hair loss. This process leads to the gradual thinning of hair, a phenomenon known as miniaturization. Therefore, reducing the formation of DHT is believed to potentially reduce hair loss.
Bioactive elements found in Japanese Ramie
Japanese ramie is rich in beneficial components, including antioxidants such as quercitrin and rutin, as well as linoleic acid, which is known for its potential to activate the Wnt/B-catenin pathways, thereby stimulating hair growth.
While we lack precise details regarding the exact composition of the extract and do not possess any studies providing specific information in this regard, it is worth noting that a study mentioned earlier did observe hair growth in mice during their research. This promising finding suggests that Japanese ramie could serve as a potential alternative to topical DHT blockers in future studies.
Closing thoughts and verdict
I believe it’s premature to regard Japanese ramie extract as a hair loss treatment at this time. Although its anti-androgenic properties hold promise, there is a lack of scientific studies confirming its effects on humans.
Precautions & side effects
- Allergies: if you have known allergies to similar plant-based extracts or components, exercise caution when using Japanese ramie extract. Especially to the family of nettles.
- Skin irritation: In some cases, topical application of Japanese ramie extract may cause skin irritation, redness, or itching. Perform a patch test before using it extensively on your skin.